(9R,12aR)-AZD4747
CAT:
804-HY-154959A-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(9R,12aR)-AZD4747
- UNSPSC Description: (9R,12aR)-AZD4747 is a diastereomer of AZD4747 (HY-154959). AZD4747 is a selective mutant GTPase KRASG12C inhibitor with blood-brain barrier permeability. AZD4747 has the potential to study cancer[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/9r-12ar-azd4747.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: C=CC(N(C[C@@H]1COC2=C3F)CCN1CC2=CC(C#CC)=[C@@]3[C@]4=C(C=CC=C4O)Cl)=O
- Molecular Weight: 440.89
- References & Citations: [1]Kettle JG, et al. Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration. J Med Chem. 2023 Jul 13;66(13):9147-9160.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported