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9-Methylstreptimidone

CAT: 0804-HY-134090-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-134090-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all) . 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
CAS Number
51867-94-8
Product Name Alternative
Antibiotic TS 885; NSC 248958
UNSPSC
12352005
Target
Bacterial; VSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/9-methylstreptimidone.html
Smiles
O=C(CC(C[C@@H](O)CC([C@@H](C)/C=C(C)/C=C\C)=O)C1)NC1=O
Molecular Formula
C17H25NO4
Molecular Weight
307.38
References & Citations
[1]Saito, et al. Studies on a new antiviral antibiotic, 9-methylstreptimidone. I. Physicochemical and biological properties. J. Antibiot. (Tokyo) 27 (3), 206-214 (1974) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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