FA10 (light chain, Cleaved-Arg179) rabbit pAb

FA10 (light chain, Cleaved-Arg179) rabbit pAb

• Description: Catalytic activity: Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin. function: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. online information: Factor X entry, PTM: N- and O-glycosylated. PTM: The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway). PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. PTM: The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. similarity: Belongs to the peptidase S1 family. similarity: Contains 1 Gla (gamma-carboxy-glutamate) domain. similarity: Contains 1 peptidase S1 domain. similarity: Contains 2 EGF-like domains. subunit: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. tissue specificity: Plasma; synthesized in the liver.
• Synonyms: Coagulation factor X (EC 3.4.21.6;Stuart factor;Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
• Gene ID: 2159
• UniProt: P00742
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: Synthesized peptide derived from human FA10 (light chain, Cleaved-Arg179)
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:1000-2000 ELISA 1:5000-20000
• Molecular Weight: 15 53kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.