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XEN723

CAT: 0804-HY-100249-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100249-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.
CAS Number
1072803-08-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Stearoyl-CoA Desaturase (SCD)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/XEN723.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)N=C(N2CCN(CC3=CC=C(F)C=C3)C2=O)S1)NCC4=CC=CN=C4
Molecular Formula
C21H20FN5O2S
Molecular Weight
425.48
Precautions
H302, H315, H319
References & Citations
[1]Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :520-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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