HCV Core Protein

• Gene Aliases :

  HCV Core, Biotin, Hepatitis C Virus Core, Biotin Recombinant

• Reactivity :

  Hepatitis C Virus

• Target :

  HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae._x005F HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6) .

• Type :

  Protein

• Applications :

  ELISA, WB

• Purification :

  HCV Core protein was purified by proprietary chromatographic technique.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  Varies by lot. See vial for concentration.

• Format :

  Liquid// 20mM Tris-HCl (pH 8.0) and 8M Urea

• Reconstitution :

  HCV Core although stable at 4° C for 1 week, should be stored below -18° C. Please prevent freeze thaw cycles.

• Molecular Weight :

  22 kDa

• Notes :

  Formerly GWB-CE9290

• Specificity :

  Immunoreactive with sera of HCV-infected individuals.

• Protein Length :

  Recombinant

• NCBI Gene Symbol :

  HCV CORE-BIOTIN

• Gene Name URL :

  HCV Core-Biotin