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HCV Core 22kDa Protein

CAT: 0247-OPPA00931-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA00931-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
HCV Core 22kDa, Hepatitis C Virus Core 22kDa Recombinant
Reactivity
Hepatitis C Virus
Target
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6) .
Type
Protein
Sequence
Mstnpkpqrk tkrntnrrpq dvkfpgvgqi vggvyllprr gprlgvratr ktsersqprg rrqpipkarr pegrtwaqpg ypwplygneg cgwagwllsp rgsrpswgpt dprrrsrnlg kvidtltcgf adlmgyiplv gaplggaara lahgvrvled gvnyatgnlp gcsfsiflla llscltvpa.
Purification
HCV-Core protein was purified by proprietary chromatographic technique.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid. In 20mM Tris Hcl pH-8, 8M urea and 10mM beta-mercaptoethanol.
Reconstitution
HCV-Core although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
Notes
Formerly GWB-E8CF6F
Specificity
Immunoreactive with sera of HCV-infected individuals.
Protein Length
Recombinant
NCBI Gene Symbol
HCV 22KDA
Gene Name URL
HCV 22kDa