Eotaxin Protein

• Gene Aliases:

  SCYA11

• Gene ID:

  6356

• Accession Number:

  NP_002977.1

• Reactivity:

  Human

• Target:

  Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.

• Type:

  Protein

• Source:

  E. Coli

• Purification:

  Purified by proprietary chromatographic techniques

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Bioactivity:

  The activity is determined by the chemoattract of human PBE (peripheral blood eosinophils) at a concentration between 0.1-10 ng/ml corresponding to a Specific Activity of 100,000 - 10,000,000 IU/mg

• Format:

  Lyophilized// from 0.2um filtered concentrated (1.0 mg/ml) solution in 20mM PB, pH 7.4, 150mM NaCl Physical Appearance:// Sterile filtered white powderPhysical Appearance:// Sterile filtered white powder

• Reconstitution:

  2

• Molecular Weight:

  8345.9 Da

• Notes:

  Formerly GWB-7A54C5

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  EOTAXIN

• Protein Name:

  Eotaxin

• Gene Name URL:

  Eotaxin