E3 ligase Ligand 35

• Description:

  E3 ligase Ligand 35 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-27 (HY-168229) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e3-ligase-ligand-35.html

• Smiles:

  OC1=NOC([C@H](C(N2C[C@H](O)C[C@H]2C(N[C@H](C3=CC(F)=C(C#N)C=C3)C)=O)=O)C(C)C)=C1

• Molecular Formula:

  C22H25FN4O5

• Molecular Weight:

  444.46

• References & Citations:

  [1]Michael Berlin, et al. Brm targeting compounds and associated methods of use. Patents, WO2023097031, 2023-06-01.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Von Hippel-Lindau (VHL)