Products for Research Use Only
RegisterLogin

ASPN Recombinant Protein

CAT: 0247-OPCD01506-50UGSize: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OPCD01506-50UGSize:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9000-83-3
Gene Name
Asporin
Gene Aliases
4631401G09Rik; AA986886; asporin; periodontal ligament-associated protein 1; PL; Plap1; SL; Slrr1c.
Gene ID
66695
Accession Number
NP_001165952.1
Reactivity
Mouse|Mus musculus
Target
Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity (By similarity) . Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins. Inhibits the interaction between TGFB1 and TGF-beta receptor type II in the presence of heparin/heparan sulfate in vitro.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
71kDa
Protein Length
Recombinant
NCBI Gene Symbol
Aspn
Host or Source
E.coli
Protein Name
Asporin
Gene Name URL
Aspn
Nucleotide Accession Number
NM_001172481.1

Related Products

CatalogName
OACA09339-50UGASPN Antibody
OACA09339-100UGASPN Antibody
AAP42487-100UGASPN Peptide (AAP42487)
ARP42487_T100-25ULASPN Antibody - middle region
OKCD02387-96WASPN ELISA Kit (Mouse)
OKEH07599-96WASPN ELISA Kit (Bovine)
OKEH04423-96WASPN ELISA Kit (Human)
OKCD08085-96WASPN ELISA Kit (Human)
OKAN06644ASPN ELISA Kit (Human) (OKAN06644)
OKCD02387ASPN ELISA Kit (Mouse) (OKCD02387)

Alternative Products

CatalogName
PPT-10699Human ASPN Recombinant Protein
RP117605ASPN Recombinant Protein (Mouse)
RP191234ASPN Recombinant Protein (Rat)
RP047614ASPN Recombinant Protein (Human)
E45M46860M5Aspn (NM_025711) Mouse Recombinant Protein
R1043hHuman ASPN / Asporin Recombinant Protein
R1043mMouse Aspn / Asporin Recombinant Protein
R1043bBovine ASPN / Asporin Recombinant Protein
HV743012-01Recombinant Human ASPN Protein, N-His
MBS2162737-01Recombinant Asporin (ASPN)

Popular Products