Hsp47 Antibody

9007-83-4

Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

SerpinH1, Colligin, Gp46, serine proteinase inhibitor, cysteine proteinase inhibitor, collagen binding protein

871

NP_001193943

Human

Human HSP47, full length

HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.

1C4-1A6

Unconjugated

Monoclonal Antibody

WB, ICC, IF

Protein G Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

1 mg/ml

WB (1:1000), ICC/IF (1:100) ; optimal dilutions for assays should be determined by the user.

Liquid// PBS (pH 7.4) with 50% glycerol and 0.09% sodium azide

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Store at -20C. Shipping with Blue Ice or 4C.

IgG1 Kappa

Detects 47kDa.

HSP47

Mouse