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HSP47 Antibody (APC)

CAT: 0013-GTR18028612Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028612Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to Hsp47 (APC) . Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils..
Product Name Alternative
SERPINH1, HSP47, Heat shock protein 47, Serpin H1, Colligin, Collagen-binding protein, Gp46, Serine protease inhibitor J6, 47 kDa heat shock protein, serine proteinase inhibitor, cysteine proteinase inhibitor, collagen binding protein
UniProt
P50454
Reactivity
Human
Immunogen
Human HSP47, full length
Target
HSP47
Clonality
Monoclonal
Clone
1C4-1A6
Conjugation
APC
Field of Research
Cell Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100)
Molecular Weight
47kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, WB
NCBI Accession Number
NP_001193943
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG1 Kappa
Entrez
871

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