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Human DR5 Antibody

CAT: 0247-OASB01407-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OASB01407-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Tumor necrosis factor receptor superfamily member 10B
Gene Aliases
DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5
Gene ID
8795
Accession Number
NP_003833.4
Reactivity
Human
Immunogen
Recombinant DR5
Target
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
FC, ICC, WB
Purification
Affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/mL
Dilution
6 cells Induction of Apoptosis: Purified antibody 2.5 ug/mL for 12 hours (10-12% in Jurkat cells)
Reconstitution
Store at 2-8C
Notes
Formerly GWB-18A3C7
Fragment
IgG
Specificity
DR5
NCBI Gene Symbol
TNFRSF10B
Host or Source
Rabbit
Protein Name
Tumor necrosis factor receptor superfamily member 10B
Gene Name URL
TNFRSF10B
Nucleotide Accession Number
NM_003842.4

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