PRDM16 Antibody

• Gene Name:

  PR/SET domain 16

• Gene Aliases:

  CMD1LL; histone-lysine N-methyltransferase PRDM16; KMT8F; LVNC8; MDS1/EVI1-like gene 1; MEL1; PFM13; PR domain 16; PR domain containing 16; PR domain zinc finger protein 16; PR domain-containing protein 16; transcription factor MEL1.

• Gene ID:

  63976

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/CAH71530

• Reactivity:

  Human|Mouse

• Immunogen:

  PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16. The immunogen is located within amino acids 1120 - 1170 of PRDM16.

• Target:

  Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. PRDM16 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  2°C to 8°C

• Molecular Weight:

  Predicted: 109, 120, 140 kDa Observed: 140 kDa

• NCBI Gene Symbol:

  PRDM16

• Host or Source:

  Rabbit

• Protein Name:

  PR domain containing 16 [Homo sapiens]|PR domain zinc finger protein 16

• Gene Name URL:

  PRDM16

• CAS Number:

  9007-83-4