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Anti-PRDM16

CAT: 0247-ARP88173_P050Size: 100 µLDry Ice: NoHazardous: No
CAT#:0247-ARP88173_P050Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
PR domain 16
Gene Aliases
MEL1, KMT8F, LVNC8, PFM13, CMD1LL
Gene ID
63976
Swiss Prot
Q9HAZ2-4
Accession Number
NP_071397.3
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PRDM16
Target
The reciprocal translocation t (1;3) (p36; q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) . This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t (1:3) (p36, q21) -positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
DVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAP
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
120 kDa
Protein Length
1092
NCBI Gene Symbol
PRDM16
Host or Source
Rabbit
Protein Name
PR domain zinc finger protein 16
Gene Name URL
PRDM16
Nucleotide Accession Number
NM_022114.3

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