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CDC42 Antibody

CAT: 0247-OAPB00856-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00856-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Cell division cycle 42
Gene Aliases
CDC42Hs; cell division control protein 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD) ) ; dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD) ) ; G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; small GTP binding protein CDC42; TKS.
Gene ID
998
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001782
Reactivity
Bovine|Chicken|Guinea Pig|Human|Mouse|Porcine|Rat
Immunogen
CDC42 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDC42. The immunogen is located within amino acids 40 - 90 of CDC42.
Target
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity) . Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. CDC42 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
CDC42 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
CDC42
Host or Source
Chicken
Protein Name
Cell division control protein 42 homolog|cell division control protein 42 homolog isoform 1 precursor [Homo sapiens]
Gene Name URL
CDC42

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