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ANP32E Antibody

CAT: 0247-OAPB00195-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00195-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Acidic nuclear phosphoprotein 32 family member E
Gene Aliases
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member E; LANPL; LANP-L; LANP-like protein; leucine-rich acidic nuclear protein like.
Gene ID
81611
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_112182
Reactivity
Human|Mouse|Rat
Immunogen
PHAP III antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III. The immunogen is located within amino acids 200 - 250 of PHAP III.
Target
Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511) . Inhibits activity of protein phosphatase 2A (PP2A) . Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. PHAP III Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
2°C to 8°C
Molecular Weight
35 kDa
Notes
Formerly GWB-6655D6
Fragment
IgG
Specificity
PHAP III has no cross-reaction to PHAP I and PHAP I2a.
NCBI Gene Symbol
ANP32E
Host or Source
Rabbit
Protein Name
Acidic leucine-rich nuclear phosphoprotein 32 family member E|acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1 [Homo sapiens]
Gene Name URL
ANP32E
Nucleotide Accession Number
NM_001136478.3NM_001136479.2NM_001280559.1NM_001280560.1NM_030920.4