Products for Research Use Only
RegisterLogin

BACE Antibody

CAT: 0247-OAPB00100-100UGSize: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAPB00100-100UGSize:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Click here to learn more about Aviva's By-Request Conjugation Service.//here
CAS Number
9007-83-4
Gene Name
Beta-secretase 1
Gene Aliases
APP beta-secretase; asp 2; ASP2; aspartyl protease 2; BACE; beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; Beta-site amyloid precursor protein cleaving enzyme 1; beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme; HSPC104; memapsin-2; membrane-associated aspartic protease 2; transmembrane aspartic proteinase Asp2.
Gene ID
23621
Accession Number
AF190725
Reactivity
Bovine|Guinea Pig|Human|Mouse|Rat
Immunogen
Anti-BACE antibody (2253) was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BACE. The immunogen is located within the last 50 amino acids of BACE.
Target
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Ion Exchange
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse
Format
Liquid. BACE Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
BACE antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 55kD Observed: 65kD (Post-modification: 4 N-linked glycosylation)
Notes
Formerly GWB-980BE2
NCBI Gene Symbol
BACE1
Host or Source
Rabbit
Protein Name
Beta-secretase 1|Homo sapiens beta-site APP cleaving enzyme (BACE) mRNA, complete cds
Gene Name URL
BACE1
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/AF190725

Related Products

CatalogName
OKRC00187-96WOKRC00187-96W - BACE-1 ELISA Kit (Human)
OACD01886-100ULBACE2 Antibody
OACA10274-100UGBACE1 Antibody
OAAF00666-100UGBACE1 Antibody
OACD01885-1MLBACE1 Antibody
OACD01887-100ULBACE2 Antibody
OACD01886-1MLBACE2 Antibody
OACA10274-50UGBACE1 Antibody
OACD01885-100ULBACE1 Antibody
OACD01887-1MLBACE2 Antibody

Alternative Products

CatalogName
GWB-15FF67BACE Antibody

Popular Products