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BACE1 Antibody

CAT: 0247-OACD01885-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD01885-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Beta-site APP cleaving enzyme 1
Gene Aliases
APP beta-secretase; asp 2; ASP2; aspartyl protease 2; Bace; beta-secretase 1; beta-site amyloid precursor protein cleaving enzyme 1; C76936; memapsin-2; membrane-associated aspartic protease 2.
Gene ID
23821
Accession Number
NP_001139419.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Pro190 - Ala430
Target
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.82 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
56 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against bACE1. It has been selected for its ability to recognize bACE1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Bace1
Host or Source
Rabbit
Protein Name
Beta-secretase 1
Gene Name URL
Bace1
Nucleotide Accession Number
NM_001145947

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