BACE2 Antibody

CAT: 0247-OACD01886-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD01886-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
Beta-site APP-cleaving enzyme 2
Gene Aliases
1110059C24Rik; A; AEPLC; AI850424; AL; ALP56; ARP1; AS; ASP1; ASP21; aspartyl protease 1; BAE; BAE2; beta-secretase 2; beta-site amyloid precursor protein cleaving enzyme 2; CDA1; CDA13; CEA; CEAP1; DRAP; memapsin-1; membrane-associated aspartic protease 1; theta-secretase.
Gene ID
56175
Accession Number
NP_062390.3
Reactivity
Human|Mouse|Rat
Immunogen
Range: Glu156 - Val407
Target
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
56 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against bACE2. It has been selected for its ability to recognize bACE2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Bace2
Host or Source
Rabbit
Protein Name
Beta-secretase 2
Gene Name URL
Bace2
Nucleotide Accession Number
NM_019517

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