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PARP1 Antibody

CAT: 0247-OALA03334-50UGSize: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0247-OALA03334-50UGSize:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
PARP1, ADPRT, ADP-ribosyltransferase NAD (+), Adp-ribosyltransferase, ADPRT1, ARTD1, ADPRT 1, Poly (ADP-ribose) synthetase, Poly (ADP-ribosyl) transferase, PARP, Poly [ADP-ribose] polymerase 1, PADPRT-1, PARP-1, Poly (ADP-ribose) polymerase 1, Poly (ADP-ribose) polymerase, Poly[ADP-ribose] synthase 1, PPOL
Gene ID
142
Accession Number
NP_001609.2
Reactivity
Human
Immunogen
Human PARP.
Clonality
Monoclonal
Clone
A6.4.12
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
ELISA, IF, IHC, IHC-F, IHC-P, IP, WB
Purification
Protein G purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid
Buffer
PBS, 0.09% Sodium Azide
Reconstitution
Store at 4C or at -20C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Fragment
IgG1
Specificity
Recognizes poly (ADP-ribose) polymerase 1 (PARP-1), a ~116kD nuclear enzyme cleaved during apoptosis. PARP-1, a caretaker enzyme, is involved in DNA damage repair, plays roles in diabetes pathophysiology and tumor proliferation.) . As well as protecting cells from genomic instability, PARP-1 is involved in the development of both inflammatory and immune responses, and cell death by apoptosis and necrosis. Targets PARP-1, an enzyme which represents a promising target for new developments in therapeutic treatment of immune mediated diseases. PARP-1 has considerable potential for delivering selective tumor cell killing while sparing normal cells.
NCBI Gene Symbol
PARP1
Host or Source
Mouse
Gene Name URL
PARP1
Nucleotide Accession Number
NM_001618

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