Products for Research Use Only
RegisterLogin

ELANE Antibody

CAT: 0247-OAGA04232-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAGA04232-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Elastase, neutrophil expressed
Gene Aliases
GE, NE, HLE, HNE, ELA2, SCN1, PMN-E
Gene ID
1991
Accession Number
NP_001963.1
Reactivity
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human Neutrophil elastase. The exact sequence is proprietary.
Target
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN) . This gene is present in a gene cluster on chromosome 19.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
IP, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid
Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Fragment
IgG
NCBI Gene Symbol
ELANE
Host or Source
Rabbit
Protein Name
Neutrophil elastase
Gene Name URL
ELANE
Nucleotide Accession Number
NM_001972.3

Related Products

CatalogName
OPCD02890-200UGELANE Recombinant Protein
OPCD02890-50UGELANE Recombinant Protein
OCOA14352-20UGELANE Protein Lysate
OPCD02890-10UGELANE Recombinant Protein
OACA12371-100ULELANE Recombinant Antibody [2H12] (OACA12371)
OPCA04084-20UGELANE Recombinant Protein (Human)
OKBB01431-96WELANE ELISA Kit (Human)
OPCA03848-20UGELANE Recombinant Protein (Human)
OKCD06117-96WELANE ELISA Kit (Mouse)
OKEH00276-96WELANE ELISA Kit (Mouse)

Alternative Products

CatalogName
47101ELANE Antibody
MBS8567755-01ELANE Polyclonal Antibody
enz-1105ELANE

Popular Products