MAPRE1 Antibody

CAT: 0247-OACD05446-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD05446-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
Microtubule associated protein RP/EB family member 1
Gene Aliases
Adenomatous polyposis coli-binding protein EB1; APC-binding protein EB1; EB1; end-binding protein 1; microtubule-associated protein RP/EB family member 1.
Gene ID
22919
Accession Number
NP_036457.1
Reactivity
Human|Porcine
Immunogen
Range: Ala2 - Tyr268
Target
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton (PubMed:12388762, PubMed:16109370, PubMed:19632184, PubMed:21646404, PubMed:28726242, PubMed:28814570) . Promotes cytoplasmic microtubule nucleation and elongation (PubMed:12388762, PubMed:16109370, PubMed:19632184, PubMed:21646404, PubMed:28726242, PubMed:28814570) . May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (PubMed:12388762) . Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:28814570) . Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570) . Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (PubMed:28726242) . May play a role in cell migration (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
30 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against MAPRE1. It has been selected for its ability to recognize MAPRE1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
MAPRE1
Host or Source
Rabbit
Protein Name
Microtubule-associated protein RP/EB family member 1
Gene Name URL
MAPRE1
Nucleotide Accession Number
NM_012325

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