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DVL1 Antibody

CAT: 0247-OACD03133-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD03133-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Dishevelled segment polarity protein 1
Gene Aliases
Dishevelled, dsh homolog 1; dishevelled-1; DSH homolog 1; Dvl; mKIAA4029; segment polarity protein dishevelled homolog DVL-1.
Gene ID
13542
Accession Number
NP_001289271.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Arg150 - Ser332
Target
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
75 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against DVL1. It has been selected for its ability to recognize DVL1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Dvl1
Host or Source
Rabbit
Protein Name
Segment polarity protein dishevelled homolog DVL-1
Gene Name URL
Dvl1
Nucleotide Accession Number
NM_001302342

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