CD14 Antibody

• Gene Name :

  Cluster Of Differentiation 14

• Gene Aliases :

  Myeloid cell-specific leucine-rich glycoprotein.

• Reactivity :

  Human|Mouse|Porcine

• Immunogen :

  Range: Thr21 - Ala373

• Target :

  Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) . Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL (-) ) and mediates the cytokine release induced by LDL (-) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification :

  Affinity Purified; Protein A Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Molecular Weight :

  40 kDa

• Fragment :

  IgG

• Specificity :

  The antibody is a rabbit polyclonal antibody raised against CD14. It has been selected for its ability to recognize CD14 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  CD14

• Host or Source :

  Rabbit

• Protein Name :

  Monocyte differentiation antigen CD14

• Gene Name URL :

  CD14

• CAS Number :

  9007-83-4