GRPR Antibody

• Gene Name:

  Gastrin releasing peptide receptor

• Gene Aliases:

  Gastrin-releasing peptide receptor; GR; GRP-preferring bombesin receptor; GRP-R.

• Gene ID:

  14829

• Accession Number:

  NP_032203.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  Range: Met1 - Leu116

• Target:

  Receptor for gastrin-releasing peptide (GRP) (PubMed:1671171, PubMed:1707129, PubMed:9345264, PubMed:12526815, PubMed:26658875) . Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation (PubMed:26658875) . Contributes to the regulation of food intake (PubMed:12176666) . Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain (PubMed:28280205, PubMed:17653196, PubMed:26658875) . Contributes primarily to nonhistaminergic itch sensation (PubMed:28280205) . Contributes to long-term fear memory, but not normal spatial memory (PubMed:12526815) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  43 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against GRPR. It has been selected for its ability to recognize GRPR in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  Grpr

• Host or Source:

  Rabbit

• Protein Name:

  Gastrin-releasing peptide receptor

• Gene Name URL:

  Grpr

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_008177