GrpE Antibody

CAT: 0247-OAED00141-1MGSize: 1 mgDry Ice: NoHazardous: No
CAT#:0247-OAED00141-1MGSize:1 mg
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CAS Number
9007-83-4
Gene Name
Nucleotide exchange factor GrpE
Gene Aliases
B2614; ECK2610; Heat shock protein B25.3; HSP24; HSP-70 cofactor; nucleotide exchange factor GrpE.
Gene ID
947097
Accession Number
WP_001296310.1YP_670504.1
Reactivity
Escherichia coli
Immunogen
Purified E. coli GrpE.
Target
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Reconstitution
Long Term Storage : //-20C
Specificity
Recognizes bacteria GrpE. Detects a band of ~24kDa by Western blot.
NCBI Gene Symbol
GrpE
Host or Source
Rabbit
Protein Name
Protein GrpE
Gene Name URL
GrpE
Nucleotide Accession Number
NC_008253.1

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