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GRPR Recombinant Protein

CAT: 0247-OPCD00913-10UGSize: 10 µgDry Ice: NoHazardous: No
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CAT#:0247-OPCD00913-10UGSize:10 µg
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CAS Number
9000-83-3
Gene Name
Gastrin releasing peptide receptor
Gene Aliases
Gastrin-releasing peptide receptor; GR; GRP-preferring bombesin receptor; GRP-R.
Gene ID
14829
Accession Number
NP_032203.1
Reactivity
Mouse|Mus musculus
Target
Receptor for gastrin-releasing peptide (GRP) (PubMed:1671171, PubMed:1707129, PubMed:9345264, PubMed:12526815, PubMed:26658875) . Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation (PubMed:26658875) . Contributes to the regulation of food intake (PubMed:12176666) . Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain (PubMed:28280205, PubMed:17653196, PubMed:26658875) . Contributes primarily to nonhistaminergic itch sensation (PubMed:28280205) . Contributes to long-term fear memory, but not normal spatial memory (PubMed:12526815) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
43kDa
Protein Length
Recombinant
NCBI Gene Symbol
Grpr
Host or Source
E.coli
Protein Name
Gastrin-releasing peptide receptor
Gene Name URL
Grpr
Nucleotide Accession Number
NM_008177.3

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