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NMNAT2 Antibody

CAT: 0247-OACA09681-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA09681-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Nicotinamide nucleotide adenylyltransferase 2
Gene Aliases
C1orf15; NaMN adenylyltransferase 2; nicotinamide mononucleotide adenylyltransferase 2; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; nicotinate-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMN/NaMN adenylyltransferase 2; PNAT2; pyridine nucleotide adenylyltransferase 2.
Gene ID
23057
Accession Number
NP_055854
Reactivity
Human
Immunogen
Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 protein (1-153AA)
Target
Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity) . Catalyzes the formation of NAD (+) from nicotinamide mononucleotide (NMN) and ATP (PubMed:16118205, PubMed:17402747) . Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency (PubMed:16118205, PubMed:17402747) . Cannot use triazofurin monophosphate (TrMP) as substrate (PubMed:16118205, PubMed:17402747) . Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD (+) (PubMed:16118205, PubMed:17402747) . For the pyrophosphorolytic activity prefers NAD (+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively (PubMed:16118205, PubMed:17402747) . Fails to cleave phosphorylated dinucleotides NADP (+), NADPH and NaADP (+) (PubMed:16118205, PubMed:17402747) . Axon survival factor required for the maintenance of healthy axons: acts by delaying Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
NMNAT2
Host or Source
Rabbit
Protein Name
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
Gene Name URL
NMNAT2
Nucleotide Accession Number
NM_015039

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