TRPM4 Antibody

CAT: 0247-OACA08989-50ULSize: 50 µLDry Ice: NoHazardous: No
CAT#:0247-OACA08989-50ULSize:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
Transient receptor potential cation channel subfamily M member 4
Gene Aliases
Calcium-activated non-selective cation channel 1; EKVP6; hTRPM4; long transient receptor potential channel 4; LTrpC4; melastatin-4; PFHB1B; transient receptor potential cation channel subfamily M member 4; TRPM4B.
Gene ID
54795
Accession Number
NP_001182156
Reactivity
Human
Immunogen
Recombinant Human Transient receptor potential cation channel subfamily M member 4 protein (1-240AA)
Target
Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:29211723) . While it is activated by increase in intracellular Ca (2+), it is impermeable to it (PubMed:12015988) . Mediates transport of monovalent cations (Na (+) > K (+) > Cs (+) > Li (+) ), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca (2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca (2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
TRPM4
Host or Source
Rabbit
Protein Name
Transient receptor potential cation channel subfamily M member 4
Gene Name URL
TRPM4
Nucleotide Accession Number
NM_001195227

Related Products

CatalogName
OCOA09977-20UGTRPM4 Protein Lysate
OKCD08842-96WTRPM4 ELISA Kit (Mouse)
OKDD00728TRPM4 ELISA Kit (Mouse) (OKDD00728)
OKCD08842TRPM4 ELISA Kit (Mouse) (OKCD08842)
OKDD00745TRPM4 ELISA Kit (Rat) (OKDD00745)
AAP35268-100UGTRPM4 Peptide - N-terminal region (AAP35268)
OACA09168-100ULTRPM6 Antibody
OACA07804-100ULTRPM2 Antibody
OACA02918-100UGTRPM2 Antibody
OACA02918-50UGTRPM2 Antibody

Alternative Products

CatalogName
MBS7046122-01TRPM4 Antibody
MBS8566304-01TRPM4 Polyclonal Antibody
STJ112185Anti-TRPM4 antibody
CSB-CL819465HUTRPM4

Popular Products