INVS Antibody

CAT: 0247-OAAN04210-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAN04210-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Inversin
Gene Aliases
INV, NPH2, NPHP2
Gene ID
27130
Swiss Prot
Q9Y283
Accession Number
NP_055240.2
Reactivity
Human, Mouse
Immunogen
Recombinant Protein
Target
Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purification
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
118 kDa
Fragment
IgG
NCBI Gene Symbol
INVS
Host or Source
Rabbit
Protein Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
Gene Name URL
INVS
Nucleotide Accession Number
NM_014425.4

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