Products for Research Use Only
RegisterLogin

ATP2A2 Antibody

CAT: 0247-OAAJ06714-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAJ06714-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Aliases
DD, DAR, ATP2B, SERCA2
Gene ID
488
Swiss Prot
P16615
Accession Number
NP_001672
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant proteinof human ATP2A2
Target
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca2+ signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
115 kDa
NCBI Gene Symbol
ATP2A2
Host or Source
Rabbit
Protein Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Gene Name URL
ATP2A2
Nucleotide Accession Number
NM_001681

Related Products

CatalogName
OPCA01475-20UGATP2A2 Recombinant Protein
OPCD01540-200UGATP2A2 Recombinant Protein
AAP45159-100UGATP2A2 Peptide (AAP45159)
OPCD01540-50UGATP2A2 Recombinant Protein
OPCA01475-100UGATP2A2 Recombinant Protein
OPCA01475-1MGATP2A2 Recombinant Protein
OPCD01540-10UGATP2A2 Recombinant Protein
OACA12267-100ULATP2A2 Recombinant Antibody [20D1] (OACA12267)
OKEH07858-96WATP2A2 ELISA Kit (Mouse)
OKCD00996-96WATP2A2 ELISA Kit (Human)

Alternative Products

CatalogName
70R-6108ATP2A2 antibody

Popular Products