Products for Research Use Only
RegisterLogin

ATP2A2 Recombinant Protein

CAT: 0247-OPCD01540-200UGSize: 200 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OPCD01540-200UGSize:200 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9000-83-3
Gene Name
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Gene Aliases
ATP2B; ATPase Ca++ transporting cardiac muscle slow twitch 2; ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2; calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; cardiac Ca2+ ATPase; DAR; DD; endoplasmic reticulum class 1/2 Ca (2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca (2+) -ATPase 2.
Gene ID
488
Accession Number
NP_001672.1
Reactivity
Homo sapiens|Human
Target
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920) . Acts as a regulator of TNFSF11-mediated Ca (2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
78kDa
Protein Length
Recombinant
NCBI Gene Symbol
ATP2A2
Host or Source
E.coli
Protein Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Gene Name URL
ATP2A2
Nucleotide Accession Number
NM_001681.3

Related Products

CatalogName
OAAJ06714-100ULATP2A2 Antibody
OACA12267-100ULATP2A2 Recombinant Antibody [20D1] (OACA12267)
AAP45159-100UGATP2A2 Peptide (AAP45159)
OKEH07858-96WATP2A2 ELISA Kit (Mouse)
OKCD00996-96WATP2A2 ELISA Kit (Human)
ARP45159_P050-25ULATP2A2 Antibody - C-terminal region
OABB02106-100UGATP2A2 Antibody - N-terminal region
OKEH07858ATP2A2 ELISA Kit (Mouse) (OKEH07858)
ARP74405_P050-25ULATP2A2 Antibody - N-terminal region
OKCD00996ATP2A2 ELISA Kit (Human) (OKCD00996)

Alternative Products

CatalogName
PPT-10736Human ATP2A2 Recombinant Protein
E30P60838ARecombinant Human ATP2A2 Protein
HB179012-01Recombinant Human ATP2A2 Protein, N-His
E45H30268E1SERCA2 (ATP2A2) (NM_170665) Human Recombinant Protein
TMPH-03766-01ATP2A2 Protein, Human, Recombinant (C-His)
YMD18801Recombinant Mouse ATP2A2/SERCA2 Protein, C-His
ARO-P18052-01Human ATP2A2 Recombinant Protein, N-GST & C-His
QP5691-ec-10ugRecombinant Human ATP2A2 Protein, His, E.coli-10ug
QP5691-ec-50ugRecombinant Human ATP2A2 Protein, His, E.coli-50ug
PR11827Recombinant Human ATP2A2 Protein, N-GST & C-His

Popular Products