FFAR4 Antibody

• Gene Aliases:

  GT01, PGR4, BMIQ10, GPR120, GPR129, O3FAR1

• Gene ID:

  338557

• Swiss Prot:

  Q5NUL3

• Accession Number:

  NP_001182684

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human GPR120, corresponding to a region within the internal amino acids.

• Target:

  Receptor for medium and long-chain free fatty acids (FFAs) . Signals via a G (q) /G (11) -coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2) /TAB1-dependent effect, but independent of the G (q) /G (11) -coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF, ICC, P-ELISA

• Purification:

  Purified by peptide affinity chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/mL

• Format:

  Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol

• Reconstitution:

  Store at -20° C. Stable for 12 months from date of receipt.

• Molecular Weight:

  42 kDa

• Specificity:

  GPR120 Antibody detects endogenous levels of total GPR120

• NCBI Gene Symbol:

  FFAR4

• Host or Source:

  Rabbit

• Protein Name:

  Free fatty acid receptor 4

• Gene Name URL:

  FFAR4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001195755