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FFAR1 Antibody

CAT: 0247-OAAF04881-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04881-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Free fatty acid receptor 1
Gene Aliases
FFA1R; free fatty acid receptor 1; GPCR40; GPR40; G-protein coupled receptor 40.
Gene ID
2864
Swiss Prot
O14842
Accession Number
NP_005294.1
Reactivity
Human|Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human FFAR1.
Target
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1) . May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity) . Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G (q) and G (i) -mediated pathway.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
31 kDa
Notes
Formerly GWB-ASF280
Specificity
FFAR1antibodydetects endogenous levels of totalFFAR1 protein.
NCBI Gene Symbol
FFAR1
Host or Source
Rabbit
Protein Name
Free fatty acid receptor 1
Gene Name URL
FFAR1

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