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LAMA3 Antibody

CAT: 0247-OAAF03029-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF03029-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Laminin subunit alpha 3
Gene Aliases
BM600; BM600 150kD subunit; E170; epiligrin 170 kda subunit; epiligrin alpha 3 subunit; Epiligrin subunit alpha; kalinin 165kD subunit; kalinin subunit alpha; LAM3, alpha-3 subunit; laminin 5, alpha-3 subunit; laminin A3; laminin subunit alpha-3; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) ; laminin-5 alpha 3 chain; laminin-5 subunit alpha; laminin-6 subunit alpha; laminin-7 subunit alpha; LAMNA; LOCS; nicein 150kD subunit; nicein subunit alpha.
Gene ID
3909
Swiss Prot
Q16787
Accession Number
NP_000218.2
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620
Target
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Dilution
The optimal working dilution should be determined by the end user.
Homology
Human; Mouse; Rat
Format
Liquid// PBS (without Mg2+ and Ca2+), pH 7.4, 0.5% BSA, 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20° C for 1 year.
Notes
Formerly GWB-ASE183
Specificity
LAMA3 antibody detects endogenous levels of total LAMA3 protein.
NCBI Gene Symbol
LAMA3
Host or Source
Rabbit
Protein Name
Laminin subunit alpha-3
Gene Name URL
LAMA3

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