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IGFBP3 Antibody (Phospho-Ser183)

CAT: 0247-OAAF00227-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF00227-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Insulin like growth factor binding protein 3
Gene Aliases
Acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; insulin-like growth factor-binding protein 3.
Gene ID
3486
Swiss Prot
P17936
Accession Number
NP_000589.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IGFBP-3 around the phosphorylation site of Ser183.
Target
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
31 kDa
Notes
Formerly GWB-ASB491
Specificity
IGFBP-3 (Phospho-Ser183) antibody detects endogenous levels of IGFBP-3 only when phosphorylated at serine 183.
NCBI Gene Symbol
IGFBP3
Host or Source
Rabbit
Protein Name
Insulin-like growth factor-binding protein 3
Gene Name URL
IGFBP3

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