IGFBP3 Antibody

• Gene Name:

  Insulin like growth factor binding protein 3

• Gene Aliases:

  Acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; insulin-like growth factor-binding protein 3.

• Gene ID:

  3486

• Swiss Prot:

  P17936

• Accession Number:

  NP_000589.2

• Reactivity:

  Human|Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human IGFBP-3.

• Target:

  IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid.// PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Reconstitution:

  -20°C

• Molecular Weight:

  31 kDa

• Notes:

  Formerly GWB-ASC516

• Fragment:

  IgG

• Specificity:

  IGFBP-3 (Ab-183) antibody detects endogenous levels of total IGFBP-3 protein.

• NCBI Gene Symbol:

  IGFBP3

• Host or Source:

  Rabbit

• Protein Name:

  Insulin-like growth factor-binding protein 3

• Gene Name URL:

  IGFBP3

• CAS Number:

  9007-83-4