CD3E Antibody

• Gene Name:

  CD3e molecule

• Gene Aliases:

  T3E, TCRE, IMD18

• Gene ID:

  916

• Swiss Prot:

  P07766

• Accession Number:

  NP_000724.1

• Reactivity:

  Human, Mouse

• Immunogen:

  This CD3 antibody is generated from mouse immunized with human CD3.

• Target:

  The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

• Clonality:

  Monoclonal

• Clone:

  OKT3

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Protein G column purification, followed by dialysis against PBS

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  490 ug/mL

• Homology:

  Human, Mouse

• Format:

  Liquid

• Reconstitution:

  Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  23 kDa

• Fragment:

  IgG2a

• NCBI Gene Symbol:

  CD3E

• Host or Source:

  Mouse

• Gene Name URL:

  CD3E

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000733.3