RFC1 Antibody - middle region

• Gene Name:

  Replication factor C (activator 1) 1, 145kDa

• Gene Aliases:

  A1, RFC, PO-GA, RECC1, CANVAS, MHCBFB, RFC140

• Gene ID:

  5981

• Swiss Prot:

  P35251-2

• Accession Number:

  NP_002904

• Reactivity:

  Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human RFC1

• Target:

  The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.

• Partner Proteins:

  SPRTN; UBC; PCNA; RPA3; RPA2; RPA1; YWHAQ; SMC1A; RFC4; NOTCH1; WDR18; RBM14; RFC5; RFC3; RFC2; LAMP2; MYOC; SIRT7; SUMO2; HDGF; RAD17; CSNK2B; tat; SAP25; ZSCAN1; SSBP3; PMS1; CEBPA; BRCA1; RFC1; BRD4; HDAC1; CASP3; TCEAL1; CCND1; RELA; CDK4; CHTF18; SMA

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  AQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSL

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  128kDa

• Protein Length:

  1147

• NCBI Gene Symbol:

  RFC1

• Host or Source:

  Rabbit

• Protein Name:

  Replication factor C subunit 1

• Gene Name URL:

  RFC1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_002913