RFC1 Antibody - middle region: Biotin (ARP56522_P050-Biotin)

• Gene Name:

  Replication factor C (activator 1) 1, 145kDa

• Gene Aliases:

  A1, RFC, PO-GA, RECC1, CANVAS, MHCBFB, RFC140

• Gene ID:

  5981

• Swiss Prot:

  P35251-2

• Accession Number:

  NP_002904

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human RFC1

• Target:

  The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.

• Partner Proteins:

  SPRTN; UBC; PCNA; RPA3; RPA2; RPA1; YWHAQ; SMC1A; RFC4; NOTCH1; WDR18; RBM14; RFC5; RFC3; RFC2; LAMP2; MYOC; SIRT7; SUMO2; HDGF; RAD17; CSNK2B; tat; SAP25; ZSCAN1; SSBP3; PMS1; CEBPA; BRCA1; RFC1; BRD4; HDAC1; CASP3; TCEAL1; CCND1; RELA; CDK4; CHTF18; SMA

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  128kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  1147

• NCBI Gene Symbol:

  RFC1

• Protein Name:

  Replication factor C subunit 1

• Nucleotide Accession Number:

  NM_002913