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EZH2 (ARP38470_P050)

CAT: 0247-ARP38470_P050Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP38470_P050Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
Enhancer of zeste homolog 2 (Drosophila)
Gene Aliases
WVS, ENX1, KMT6, WVS2, ENX-1, EZH2b, KMT6A
Gene ID
2146
Swiss Prot
Q15910
Accession Number
NP_004447.2
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2
Target
EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
Partner Proteins
FBXW11; CEP63; HOTAIR; EED; BRCA1; SUZ12; SNAI1; SRSF1; SDCBP; UPF1; RBBP7; RBBP4; RAP1GAP; PLEC; PKM; POTEE; DHX36; AEBP2; HIST4H4; KLC4; SERPINB12; PHF5A; FIP1L1; FBXL18; CPSF7; DDX3X; DBN1; SLC25A10; COPB1; CALML3; ATP5C1; ATP5B; ATP2A2; ARG1; AR; ANXA
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQE
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
85kDa
Specificity
From peptide immunogen, will recognize all 5 isoforms.
Protein Length
751
NCBI Gene Symbol
EZH2
Host or Source
Rabbit
Protein Name
Histone-lysine N-methyltransferase EZH2
Gene Name URL
EZH2
Nucleotide Accession Number
NM_001203247

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