PKA C-alpha Recombinant Rabbit Monoclonal Antibody [PSH08-57]

PKA C-alpha Recombinant Rabbit Monoclonal Antibody [PSH08-57]

• Description: The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene. This enzyme is responsible for phosphorylating other proteins and substrates, changing their activity. Protein kinase A catalytic subunit (PKA Cα) is a member of the AGC kinase family (protein kinases A, G, and C), and contributes to the control of cellular processes that include glucose metabolism, cell division, and contextual memory. PKA Cα is part of a larger protein complex that is responsible for controlling when and where proteins are phosphorylated. Defective regulation of PKA holoenzyme activity has been linked to the progression of cardiovascular disease, certain endocrine disorders and cancers.
• Product Name Alternative: cAMP-dependent protein kinase catalytic subunit alpha PKA C-alpha PRKACA PKACA
• Abbreviation: cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACA, PKACA
• CAS Number: 9000-83-3
• Swiss Prot: P17612 Human, P05132 Mouse, P27791 Rat
• Cellular Locus: Cytoplasm, Cell membrane, Membranem Nucleus, Mitochondrion.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Monkey
• Immunogen: Recombinant protein within human PKA C-alpha aa 1-351.
• Isotype: IgG
• Clone: PSH08-57
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC
• Positive Control: HEK-293 cell lysate, PC-3 cell lysate, MCF7 cell lysate, PC-12 cell lysate, C6 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, human brain tissue, human stomach tissue, human testis tissue, mouse testis tissue, rat testis tissue, MCF7, NIH/3T3, C6, HEK-293.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:50 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 41 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes