Falnidamol

• Target :

  EGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis

• Purity :

  0.9882

• Bioactivity :

  Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. It displays >1000-fold lower potency against ErbB2 (IC50=3.4 ?M) and other related tyrosine kinases (IC50>10 ?M) . Falnidamol is a pyrimido-pyrimidine compound and exhibits anti-cancer activity.

• Smiles :

  CN1CCC(CC1)Nc1ncc2ncnc(Nc3ccc(F)c(Cl)c3)c2n1

• Molecular Formula :

  C18H19ClFN7

• Molecular Weight :

  387.84

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  196612-93-8