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Rabbit anti Human MGMT

CAT: 0579-X2730PSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0579-X2730PSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The MGMT enzyme is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
CAS Number
9007-83-4
Synonyms
Methylated-DNA--Protein-Cysteine Methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
UniProt
P16455U
Host
Rabbit
Species Reactivity
Human
Isotype
Ig
Conjugation
Affinity Purified
Type
Antigen Immunoaffinity Purified Polyclonal
Applications
WB, IHC
Field of Research
Signal Transduction
Purification Method
Antigen Immunoaffinity Purification
Assay Principle
Optimal concentration should be evaluated by serial dilutions.
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

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