Rabbit anti Human LNX2

• Background:

  Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.

• Synonyms:

  Numb-Binding Protein 2, PDZ Domain-containing RING finger Protein 1

• UniProt:

  Q8N448

• Host:

  Rabbit

• Species Reactivity:

  Human

• Conjugation:

  Affinity Purified

• Type:

  Antigen Immunoaffinity Purified Polyclonal

• Applications:

  WB

• Field of Research:

  Signal Transduction

• Purification Method:

  Antigen Immunoaffiinity Purification

• Assay Principle:

  Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.

• Stability:

  See expiration date on vial

• Concentration:

  Lot specific, See vial

• Form:

  Provided as solution in phosphate buffered saline with 0,08% sodium azide

• Precautions:

  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

• References & Citations:

  1. Rice, D.S., et al. 'The Lnx family proteins function as molecular scaffolds for Numb family proteins.' Mol Cell Neurosci. 2001 Nov;18(5):525-40. 2. Mirza, M., et al. 'The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2).' Exp Cell Res. 2005 Sep 10;309(1):110-20.

• Shipping Conditions:

  Ambient Temperature, freeze upon arrival

• Storage Conditions:

  Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

• Functional Analysis:

  WB

• CAS Number:

  9007-83-4