Rabbit anti Human Lass3

• Background:

  LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to Humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.

• Synonyms:

  LAG1 longevity assurance homolog 3

• UniProt:

  Q8IU89

• Host:

  Rabbit

• Species Reactivity:

  Human

• Conjugation:

  Affinity Purified

• Type:

  Antigen Immunoaffinity Purified Polyclonal

• Applications:

  WB

• Purification Method:

  Antigen Immunoaffiinity Purification

• Assay Principle:

  Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.

• Stability:

  See expiration date on vial

• Concentration:

  Lot specific, See vial

• Form:

  Provided as a solution in Tris buffered saline with 0,08% sodium azide, 10mM MgCl2, 10mM ammonium sulfate, and 0,2% lactose.

• Precautions:

  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

• References & Citations:

  Mizutani, Y., et al. 'LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity.' Biochem. J., 2006, 398, 531-538.

• Shipping Conditions:

  Ambient Temperature, freeze upon arrival

• Storage Conditions:

  Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

• Functional Analysis:

  WB

• CAS Number:

  9007-83-4