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Amyloid Precursor C-Terminal Peptide

CAT: 0931-TP2177-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2177-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others
Related Pathways
Others
Bioactivity
Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. So it is a possible contributor to Alzheimer′s pathogenesis through MAPKs- and NF-κB-dependent astrocytosis.
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NCC(=O)N[C@@]([H])(C/C1=C/C=C(/O)C=C1)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N2CCC[C@@]2([H])C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C/C3=C/C=C(/O)C=C3)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C/C4=C/C=CC=C4)C(=O)N[C@@]([H])(C/C5=C/C=CC=C5)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC[S]C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)O)[C@@](O)(C)[H]
Molecular Formula
C86H118N20O27S1
Molecular Weight
1896.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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