RABBIT ANTI AMYLOID PRECURSOR PROTEIN (C-TERMINAL)

• NCBI Gene ID:

  351

• Reactivity:

  Human, Mouse, Rat

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item recognises both intact APP, and also the C99 fragment generated by Beta-secretase.The sequence recognised by this antibody corresponds to amino acids 85-99 of the C99 fragment. The C99 fragment itself is a substrate for gamma-secretase to generate the 4kD beta amyloid peptide which is found in the brains of Alzheimer's disease patients. APP also inhibits Notch signaling through it's interaction with NUMB.

• Other Gene Names:

  [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)]

• Short Name:

  [AMYLOID PRECURSOR PROTEIN]

• Other Product Names:

  [amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; alzheimer disease amyloid protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II]

• NCBI GI Number:

  4502167

• NCBI Accession Number:

  NP_000475.1

• NCBI GB Accession Number:

  NM_000484.3

• Uniprot Accession Number:

  P05067

• CAS Number:

  9007-83-4