TRV-120027

CAT: 0931-TP2158L-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-TP2158L-01Size:100 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1234510-46-3
Target
RAAS|||Arrestin|||Others
Related Pathways
Others|||GPCR/G Protein|||Endocrinology/Hormones
Bioactivity
TRV120027 is a ?-arrestin-1-biased agonist of the angiotensin II receptor type 1. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility.
Smiles
[H][C@](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)([C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(O)=O
Molecular Formula
C43H67N13O10
Molecular Weight
926.09
Shipping Conditions
Cool pack
Storage Temperature
-20°C