Pep2-SVKI

• Target :

  IGluR

• Related Pathways :

  Membrane transporter/Ion channel|||Neuroscience

• Bioactivity :

  Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1) . Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD) .

• Smiles :

  [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)CO)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O

• Molecular Formula :

  C60H93N13O18

• Molecular Weight :

  1284.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  328944-75-8