Pep2-SVKI

CAT: 0931-MF-0040331Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0040331Size:2 mg
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CAS Number
328944-75-8
Target
IGluR
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Bioactivity
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1) . Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD) .
Smiles
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)CO)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O
Molecular Formula
C60H93N13O18
Molecular Weight
1284.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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